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Research in stem cell science has grown by leaps and bounds in the last decade and scientists are excited by the advances made but admit that these are still relatively inefficient. The enthusiasm stems from the fact that Dr. Robert Lanza, chief of Advance Cell Technology and his team has created stem cells using human skin cells and four proteins. The innovation builds on the breakthrough discovery in 2006 by Shinya Yamanaka, who also coaxed human skin cells to revert to pristine, embryonic state introducing four key genes into the cells, piggyback on viruses. However, some of those genes are known to cause cancer, which made Yamanaka’s stem cells, known as induced pluripotent stem cells, or iPS cells unsuitable for human use.

So far, Dr. Robert Lanza says the iPS generated using their method is equivalent to those made using Yamanaka’s strategy. In lab tests involving the regrowing of certain cells found in the retina, these cells flourish robustly and promise potential treatment to replace damaged eye cells in conditions such as pigmentosa or macular degeneration.

Dr. Arnold Kriegstein, director of the Institute for Regeneration Medicine at the University of California, San Francisco, notes that “the ability to make cell lines from patients with any risk of genetic alteration is a significant step, but the efficiency of 0.001% of cells is low, and even that took two months to achieve,” referring to the fact that only a tiny percentage of skin cells in the study transformed into iPS cells over two months of lab work by Dr Robert Lanza and his team of scientists.